Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1997-02-27
1999-07-20
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 9, 514 18, 530317, 530330, 530331, A61K 3800, C07K 500, C07K 700, C07K 1700
Patent
active
059256176
ABSTRACT:
The present invention is to provide a prophylactic/therapeutic composition for the secondary cataract comprising a polypeptide having an inhibitory activity of cell adhesion and a lactic acid-glycolic acid polymer.
The composition of the present invention inhibits adhesion and extension of lens epithelial cells onto the posterior lens capsule after extraction of lens and is useful as a prophylactic/therapeutic composition for the secondary cataract in the clinical point of view.
REFERENCES:
patent: 4792525 (1988-12-01), Ruoslahti et al.
patent: 5629294 (1997-05-01), diZerega et al.
T. Sasabe et al., "Differential Effects of Fibronectin-Derived Oligopeptides on the Attachment of Rabbit Lens Epithelial Cells in vitro", Ophthalmic Research, 1996, 28, pp. 201-208.
Igari Yasutaka
Kamei Shigeru
Kiritoshi Akira
Sasabe Tetsuo
Watanabe Noriko
Marshall S. G.
Senju Pharmaceutical Co. Ltd.
Tsang Cecilia J.
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