Promotion of protein synthesis and suppression of urea formation

Details Promotion of protein synthesis and suppression of urea formation Promotion of protein synthesis and suppression of urea formation

1976-03-23

1978-07-11

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

424317, 424319, A61K 3140, A61K 3119, A61K 31195

Patent

active

041001613

ABSTRACT:
Compositions containing the keto analogs of certain of the amino acids essential for humans are therapeutically employed in the treatment of patients confined to low or restricted protein diet, particularly in cases of renal diseases. These analogs promote protein synthesis in the human body and suppress undesired urea formation, partly as a result of altering the body's mechanisms for conserving protein.

REFERENCES:
patent: 2457820 (1949-01-01), Howe et al.
patent: 3764703 (1973-10-01), Bergstrom et al.
Chemical Abstracts 81:54452q (1974).
Chemical Abstracts 82:144958j (1975).
Richards et al., Lancet pp. 128-134 (7-17-71).
Richards et al., Lancet pp. 841-849 (10-21-67).
Rudman J. of Clinical Invest. 50, pp. 90-96, (1971).

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