Promotion of high specificity molecular assembly

Details Promotion of high specificity molecular assembly Promotion of high specificity molecular assembly

1990-11-30

1995-12-12

Jones, W. Gary

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

435 6, 435 681, 435 693, 435 701, 435820, 436501, 530350, 530358, 5303871, 536 221, 536 253, 935 78, C07H 2100, C12P 100

Patent

active

054749115

ABSTRACT:
This invention relates to an improvement in promoting the rate of association for high specificity binding pairs used in a variety of industrial, research and medical applications. These pairs include enzyme/substrate, complementary polynucleotide and antibody/antigen combinations. In one specific embodiment, this invention relates to the acceleration of nucleic acid hybridization by heterogeneous nuclear ribonucleoproteins [hnRNPs]. In another specific embodiment, this invention relates to the acceleration of nucleic acid hybridization by a cationic detergent.

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