Promoters for expression in modified vaccinia virus Ankara

Details Promoters for expression in modified vaccinia virus Ankara Promoters for expression in modified vaccinia virus Ankara

2004-10-27

2010-10-19

Joike, Michele K (Department: 1636)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S069100, C435S320100, C536S023100

Reexamination Certificate

active

07816508

ABSTRACT:
The invention concerns promoters, in particular for the expression of genes and/or coding sequences in vaccinia viruses such as Modified vaccinia virus Ankara (MVA). The invention further concerns expression cassettes comprising said promoter, vectors comprising said expression cassettes as well as pharmaceutical compositions and vaccines.

REFERENCES:
patent: 6440422 (2002-08-01), Sutter et al.
patent: 6682743 (2004-01-01), Mayr
patent: WO-02/42480 (2002-05-01), None
patent: WO-03/097844 (2003-11-01), None
patent: WO-2004/015118 (2004-02-01), None
Accession No. U94848.
Antoine et al. The Complete Genomic Sequence of the Modified Vaccinia Ankara Strain: Comparison with Other Orthopoxviruses. Virology 244: 365-396, 1998.
Shida et al.; Inprovement in 5′ Upstream of A-1 Type Inclusion Body Gene of Pox Virus and Improvement in Extraneous Gene Manifestation Vector by 3′ -Downstream Region of Said Gene, Derwent Abstract of JP 1202288, Aug. 15, 1989.
Mars et al.; “Characterization of Vaccinia Virus Early Promoters and Evaluation of Their Informational Content”; Journal of Molecular Biology, vol. 198, No. 4, pp. 619-631, (1987).
Chakrabarti et al.; Compact, Synthetic, Vaccinia Virus Early/Late Promoter for Protein Expression, Biotechniques, vol. 23, No. 6, pp. 1094-1097, (1997).
Davison and Moss. Structure of Vaccinia Virus Late Promoters. J. Mol. Biol, 210:771-784 (1989).

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