Promoter region for DNA sequences which encode the precursor of

Details Promoter region for DNA sequences which encode the precursor of Promoter region for DNA sequences which encode the precursor of

1989-08-14

1992-09-29

Weimar, Elizabeth C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4353201, 935 6, C07H 1512, C12N 1500

Patent

active

051515083

ABSTRACT:
The present invention is related to the promoter of the gene for the human precursor of the Alzheimer's Disease A4 amyloid protein (PAD gene).
Another object of the present invention is the use of this promoter in a method of establishing a screening model for the Alzheimer's Disease. Thus the present invention is also related to a vector useful in the transfection of cells and the cells and animals transfected therewith.

REFERENCES:
Kang et al. (1987) The Precursor to Alzheimer's Disease Amyloid A4 protein . . . Nature 325, 733-736.
Scangos et al. (1987) Gene Transfer into Mice, Advances in Gentics vol. 24, 285-322.
Riccio et al. (1985) The Human Urokinase-plasminogen activator gene and its promoter, Nucleic Acids Res. 13, 2759-2771.

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