Prolonged storage of red blood cells and composition

Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...

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604 4, A01N 102

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active

061500852

ABSTRACT:
Novel additive solutions useful for the storage of human red blood cells (RBCs) under refrigerated conditions are disclosed. Also disclosed is a method of using the additive solutions in an appropriate volume to preserve RBCs at about 1 to 6.degree. C. for up to 10 weeks. Additive solutions and processes in accordance with the present invention allow the viable storage of human RBCs for an extended period of time in a solution which is directly infusible in humans.

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Hogman, C. F. et al. (1995) Shall red cell units stand upright, lie flat or be mixed during storage? In vitro studies of red cells collected in 0.5 CPD and stored in RAS2 (Erythrosol.RTM.). Transfus. Sci. 16:193-199.
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American Association of Blood Banks Technical Manual, Walker, Richard H., editor in Chief, 1993, p. 52.

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