Prolonged-release pharmaceutical compositions for oral administr

Details Prolonged-release pharmaceutical compositions for oral administr Prolonged-release pharmaceutical compositions for oral administr

1978-01-13

1979-05-22

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 19, A61K 936, A61K 922

Patent

active

041559932

ABSTRACT:
An orally administrable pharmaceutical composition comprises a dosage of the acid oralate of naftidrofuryl having a prolonged release coating which is a film formed from hydroxypropyl methyl cellulose and ethyl cellulose, the content of ethyl cellulose being between 30 and 50% and containing 8 to 15% of propylene glycol relative to the total of the cellulose derivatives.
The composition, having prolonged therapeutic activity is capable of being used in the treatment of arterial diseases in limbs, circulatory disorders in the hands and feet, cerebral vascular disorders and diffuse circulatory insufficiency with elderly people.

REFERENCES:
patent: 2887440 (1959-05-01), Greminger et al.
patent: 3247066 (1966-04-01), Milosovich
patent: 3334096 (1967-08-01), Szarvasi et al.
patent: 3388041 (1968-06-01), Gans et al.
patent: 3538214 (1970-11-01), Polli et al.
patent: 3835221 (1974-09-01), Fulborth et al.
patent: 3917813 (1975-11-01), Pedersen
patent: 4083949 (1978-04-01), Benedikt

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