Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-05-30
1997-01-21
Weimar, Elizabeth C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 2, 514 6, 514 21, 514964, A61K 3818, A61K 3827
Patent
active
055959717
ABSTRACT:
Prolonged parenteral release of a bioactive polypeptide at desirably effective levels can be achieved using novel compositions in which the polypeptide is present in a biocompatible oil in an unusually high proportion such as at least about 10% by weight. Also disclosed are certain metal-associated somatotropins that are useful for prolonged parenteral release of such somatotropins.
REFERENCES:
patent: 2491537 (1949-12-01), Welch
patent: 2493202 (1950-01-01), Macek
patent: 2661315 (1953-12-01), Juriat et al.
patent: 2690414 (1954-09-01), Buckwalter
patent: 2807569 (1954-01-01), Homan et al.
patent: 2902408 (1959-09-01), Bouman et al.
patent: 3118815 (1964-01-01), Li
patent: 3678027 (1972-07-01), De Jager et al.
patent: 3810881 (1974-05-01), Rittel et al.
patent: 3869549 (1975-03-01), Geller
patent: 4172138 (1979-10-01), Rhodes
patent: 4256737 (1981-03-01), Nestor et al.
patent: 4279547 (1981-07-01), Clem
patent: 4310516 (1982-01-01), Chang et al.
patent: 4328214 (1982-05-01), Rink et al.
patent: 4343789 (1982-08-01), Kawata et al.
patent: 4358439 (1982-11-01), Sieber et al.
patent: 4388307 (1983-06-01), Cavanak
patent: 4452775 (1984-06-01), Kent
patent: 4526938 (1985-07-01), Churchill et al.
patent: 4659696 (1987-04-01), Hirai et al.
patent: 4670419 (1987-06-01), Uda et al.
patent: 4968703 (1990-11-01), Humphrey et al.
patent: 5013713 (1991-05-01), Mitchell
patent: 5086041 (1992-02-01), Mitchell
patent: 5474980 (1995-12-01), Mitchell
Sokol & Sise, "The Effect of Exogenous Vasopressin and Growth Hormone on the Growth of Rats with Hereditary Hypothalamic Diabetes Insipidus," Growth 37:127-142 (1973).
Besser, et al., "Growth Hormone Release Inhibiting Hormone in Acromegaly." Brit. Med. J. 2:352-355 (1974).
Wolfson, et al., "The Development, Evaluation, and Clinical Use of Long-Acting ACTH Preparations," Proc. of the Second Clinical ACTH Conf., J. R. Mote, ed., pp. 1-29 (1951).
W. Wolfson, et al., "An Excellently Tolerated, Heat-Stable, Long Acting ACTH Preparation Suitable for Prolonged & Ambulatory Treatment," Abstracts of Papers of Thirty-Third Meeting: 11, p. 800 (1952).
W. Wolfson, and S. Fajans, "A Comparison of the Duration of Action of Various Long-Acting ACTH Preparations in Human Subjects," New Eng. Jour. Med. 246:1000-1004 (1952).
Bruce, A. Parkes, W. Perry, "Assay of ACTH on the Thymus of The Nestling Rat," Lancet, pp. 790-2793 (1952).
W. Wolfson, "The Three Subtypes of Pituitary Adrenocorticotropin," AMA Archives of Internal Med., pp. 108-147 (ca. 1953).
Thompson and Fisher, "Correlation of ACTH Assays," Endocrinol. 52:496-509 (1953).
Thompson, "Sustained Release of Parenteral Drugs," Bulletin of Parental Drug Assoc., pp. 6-16 (1960).
W. Wolfson, et al., "The Probability the Increased Secretion of Oxysteriods Does Not Fully Explain Improvement in Certain Systemic Diseases During Pregnancy," JMSMS, pp. 1019-1022 (1952).
Buckwalter and Dickison, "The Effect of Vehicle and Particle Size on the Absorption of the Intramuscular Route of Procaine Penicillin G Suspension, " J. Amer. Pharm. Assn. XLVII:661-666 (1958).
Thompson and Hecht, "Studies on a Long-Acting Vitamin B12 Preparation," Amer. J. Clin. Nutrition 7:311-317 (1959).
R. Nash, "The Pharmaceutical Suspension, Part 1", Drug & Cosmetic Industry, 97 (1965).
R. Nash, "The Pharmaceutical Suspension, Part 2," Drug & Cosmetic Industry, 98 (1966).
R. Nash, "Parenteral Suspensions," Bulletin of Parental Drug Assoc. 26:91-95 (1972).
M. Groves, "The Formulation of Parenteral Products," Parenteral Products, pp. 14-47 (1973).
Y. Chien, "Long-Acting Parenteral Drug Formulations," Jour. Parenteral Sci. & Tech. 35:106-139 (1981).
Y. Chien, Novel Drug Delivery Systems, pp. 219-247, (1982).
Y. Chien, "Syringeability of Nonaqueous Parenteral Formulations -- Development and Evaluation of a Testing Apparatus," J. Parenteral Sci. and Technol. 35:281-284.
Warner, Aluminum Carboxylates in Encyclopedia of Chemical Technology, Kirk and Ottmer (1978).
Lippe, et al., "Use of Growth Hormone Gel," archives of Disease in Childhood 54:609-613 (1979).
Fara, "Recent Advances in Parenteral Drug Delivery Systems," J. Parenteral Sci. and Technol. 37:20-25 (1983).
"Continuous Elevation of Blood Growth Hormone Concentrations by Beeswax Implant" Davis et al. J. Dairy Science 66 1980-1982 (1983).
"The Development, Evaluation and Clinical Use of Long-Acting ACTH Preparations" Wolfson et al. Proceedings of Second Clinical ACTH Conference, vol. II, Part I, pp. 1-29 (1951).
Remington's Pharmaceutical Sciences, 16th Ed. 1980, pp. XIII and 1609/1610.
The Concise Oxford Dictionary, 1976, p. 801.
"Estimation of Growth Hormone Secretion Rate in Cattle", J. Animal Science 29 (1969), pp. 341-344, M. K. Youself et al.
"Effect of Placental Gonadotropin on Pregnancy Rate in the Bovine", J. Animal Science 36,6, 1973, pp. 1129-1136, J. F. Wagner et al.
Physical Pharmaceutics - E. Shotton & K. Ridgway, Clarenden Press, Oxford, 1974, pp. 69 and 70.
"Long-Acting Parenteral Drug Formulations", J. Parenteral Science and Technology, vol. 15, No. 3, 1981, pp. 106-139, Yie W. Chien.
Cooper and Gunn's Dispensing For Pharmaceutical Students, 12th Ed., Pitman Medical, 1975, pp. 354-356.
"Effect of Growth Hormone on Milk Production and Feed Utilization in Dairy Cows", J. Dairy Science 56(5), 575-580 (1973), L. J. Machlin.
Dispensing of Medication, Ed. Hoover, 39-85 (1976).
Drug Design, vol. 4, Ariens, 75-92 (1973), particularly Table 1, p. 87.
Formulation of Veterinary Dosage Forms, vol. 17, Ed. Blodinger, 1-70 (1983).
Galenica 2 Biopharmacie, Paris, 1978, pp. 517-518.
Moore et al., 34 Int'l. J. Pharm. 35-43 (1986) at p. 37.
Beck George R.
Bond Gary M.
Gupta Anish
Monsanto Company
Weimar Elizabeth C.
LandOfFree
Prolonged release of biologically active polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Prolonged release of biologically active polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prolonged release of biologically active polypeptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2324257