Prolonged release microparticle preparation and production of th

Details Prolonged release microparticle preparation and production of th Prolonged release microparticle preparation and production of th

1995-02-13

1997-07-29

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

264 432, 264 46, 424426, 424463, 424493, 4284022, 42840221, 514963, A61K 958, A61K 962, B01J 1304

Patent

active

056519907

ABSTRACT:
A novel microparticle preparation comprising microparticles of a polymer which contain a drug and are coated with a film of an agent for preventing aggregation of the microparticles is disclosed. The preparation is produced by spraying a solution of a polymer containing a drug and an aqueous solution of an agent for preventing aggregation of the microparticles separately from different nozzles and contacting them with each other in a spray dryer.

REFERENCES:
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patent: 5093130 (1992-03-01), Fujii et al.
Derwent's Documentation Abstracts re: EP 0,315,875 (1992).
Bodmeier et al., "Preparation of Biodegradable Poly(.+-.)lactide Microparticles Using a Spray-Drying Technique", J. Pharm. Pharmacol., 1988, vol. 40, pp. 754-757.

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