Prolonged release microcapsules

Details Prolonged release microcapsules Prolonged release microcapsules

1994-01-31

1996-01-02

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424461, 424489, 6048911, A61K 952, A61K 962

Patent

active

054806569

ABSTRACT:
This invention provides a microcapsule designed for zero order release of a physiologically active polypeptide over a period of at least two months, which is produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing about 20 to 70% (w/w) of said polypeptide and an oil layer containing a copolymer or homopolymer having a weight-average molecular weight of 7,000 to 30,000, wherein the composition ratio of lactic acid/glycolic acid in the copolymer or homopolymer is 80/10 to 100/0, and then subjecting said water-in oil emulsion to microencapsulation.

REFERENCES:
patent: 4652441 (1987-03-01), Okada et al.
patent: 4711782 (1987-12-01), Okada et al.
patent: 4895724 (1990-01-01), Cardinal et al.
patent: 4897268 (1990-01-01), Tice et al.
patent: 4917893 (1990-04-01), Okada et al.
patent: 4954298 (1990-09-01), Yamamoto et al.
Journal of Pharmaceutical Science, vol. 73, No. 9, Sep. 1984, pp. 1294-1297.
Drug Development and Industrial Pharmacy, 16(16), pp. 2353-2367, 1990.

Affiliated with

Also associated with

Rating

Prolonged release microcapsules does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Prolonged release microcapsules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prolonged release microcapsules will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-233565