Prolonged-release liquid type of pharmaceutical preparation comp

Details Prolonged-release liquid type of pharmaceutical preparation comp Prolonged-release liquid type of pharmaceutical preparation comp

1993-03-31

1994-11-29

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424 7812, 424 7813, A61K 3174, A61K 908

Patent

active

053688520

ABSTRACT:
The present invention provides a prolonged-release liquid type of pharmaceutical preparation prepared by coating a pharmaceutically active drug-ion exchange resin complex which was treated previously with an impregnating agent, with a water permeable diffusion barrier material, followed by suspending the coated complex in a solution containing preservatives. The formulation of the present invention does not develop the rupture of the diffusion barrier film even in a solution containing preservatives. Therefore the formulation of the present invention is a prolonged-release liquid type of pharmaceutical preparation which is stable and does not lose the controlled release of the active ingredient.

REFERENCES:
patent: 4221778 (1980-09-01), Raghunathan
patent: 4996047 (1991-02-01), Kelleher et al.
patent: 5032393 (1991-07-01), Douglas et al.

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