Prolonged release bioadhesive therapeutic systems

Details Prolonged release bioadhesive therapeutic systems Prolonged release bioadhesive therapeutic systems

2005-07-12

2005-07-12

Spear, James M. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S422000, C424S430000, C424S434000, C424S439000, C424S464000, C424S465000

Reexamination Certificate

active

06916485

ABSTRACT:
The present invention concerns a prolonged release bioadhesive mucosal therapeutic system containing at least one active principle, with an active dissolution test of more than 70% over 8 hours and to a method for its preparation. The bioadhesive therapeutic system may be in tablet form and may contain quantities of natural proteins representing at least 50% by weight of active principle and at least 20% by weight of the tablet, between 10% and 20% of a hydrophilic polymer, and compression excipients, and may contain between 4% and 10% of an alkali metal alkylsulphate to reinforce the local availability of active principle and between 0.1% and 1% of a monohydrate sugar.

REFERENCES:
patent: 5362498 (1994-11-01), Aiache
patent: 0 542 824 (1995-08-01), None
patent: WO 97/15296 (1997-05-01), None
C. Hermant et al., Med.Mal.Infect., vol. 27, ppl. 715-718 (1997).
J. Vasquez, Pharmacotherapy, vol. 19(1), pp. 76-87 (1999).
D. Greenspan et al., Lancet, vol. 348, pp. 729-733 (1996).
M. Weinert et al., Annals of Internal Medicine, vol. 125, pp. 485-496 (1996).
JE Clarkson, Cochrane Database Syst. Rev (2) :CD000978 (2000).
J. A. Kovacs et al., The New England Journal of Medicine, pp. 1416-1429 (May 11, 2000).
N. Imam et al., The American Journal of Medicine, vol. 89, pp. 142-146 (1990).
R. V. Martin-Algarra et al., Pharmaceutical Research, vol. 11(7), pp. 1042-1047 (1994).
F. C. Odds, Clinical Research Reviews, vol. 1, pp. 231-232 (1981).

Affiliated with

Also associated with

Rating

Prolonged release bioadhesive therapeutic systems does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Prolonged release bioadhesive therapeutic systems, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prolonged release bioadhesive therapeutic systems will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3369139