Prolonged efficacy of islet neogenesis therapy methods with...

Details Prolonged efficacy of islet neogenesis therapy methods with... Prolonged efficacy of islet neogenesis therapy methods with...

2006-01-31

2006-01-31

Kemmerer, Elizabeth (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S198100, C514S866000, C530S309000, C530S399000

Reexamination Certificate

active

06992060

ABSTRACT:
Compositions and methods are provided for achieving in vivo islet cell regeneration in subjects with preexisting diabetes. The methods comprise short term treatment with a composition having a gastrin/cholecystokinin receptor ligand and an EGF receptor ligand. Treatment with such a composition for a short term resulted in a prolonged period of increased insulin release, decreased fasting blood glucose, and improved glucose tolerance, the prolonged efficacy, the period being considered from the time of cessation of treatment.

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