Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1988-10-28
1990-07-24
Epstein, Henry F.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424449, 424486, 128156, 128632, 131335, A61L 1500
Patent
active
049434357
ABSTRACT:
A transdermal patch for delivering nicotine for prolonged periods of 12-24 hours. The patch includes a rate-controlling membrane or monolith to keep the nicotine flux within useful and safe limits. The patch is typically replaced once a day, and can be used for smoking cessation therapy or in other situations where systemic nicotine delivery is indicated.
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J. E. Rose et al., "Transdermal Administration of Nicotine,"Drug and Alcohol Dep., 13, 209-213, 1984.
J. F. Komerska, "Urethane Films--Transdermal Opportunities," J. Plastic Film and Sheeting, 3 58-64; 1987.
Baker Richard W.
Huang Carl
Kochinke Frank
Castro A. J.
Epstein Henry F.
Farrant J.
Pharmetrix Corporation
Ryan P. S.
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