Prolonged-action multiple-layer tablets

Details Prolonged-action multiple-layer tablets Prolonged-action multiple-layer tablets

1982-08-27

1984-06-12

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 14, 424 19, 424 20, 424 21, 424 22, 424 38, 424361, 424362, A61K 924, A61K 928, A61K 942

Patent

active

044541082

ABSTRACT:
A prolonged-action multiple-layer tablet having an increased rate of dissolution of the active ingredient from a given point of time onward is disclosed. The tablet comprises layer A made of an intimate mixture of a water-insoluble wax that has an average particle size of 10 .mu.m or less and which is solid at ordinary temperatures, a disintegrator and a binder, and layer B made of an intimate mixture of a water-insoluble wax that has an average particle size of 10 .mu.m or less and which is solid at ordinary temperatures, a disintegrator, a binder and the active ingredient. In the tablet, a quick-release layer containing the active ingredient may be formed on either layer A or B.

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