Proline derivatives and use thereof as drugs

Details Proline derivatives and use thereof as drugs Proline derivatives and use thereof as drugs

2006-06-13

2006-06-13

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S365000, C548S200000, C548S518000

Reexamination Certificate

active

07060722

ABSTRACT:
The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products.The present inventors have found that derivatives having a substituent introduced into the γ-position of proline represented by the formula (I)wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.

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