Proline derivatives and the use thereof as drugs

Details Proline derivatives and the use thereof as drugs Proline derivatives and the use thereof as drugs

2006-07-11

2006-07-11

Shameem, Golam M M (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S358000, C544S359000, C544S371000, C548S190000, C548S194000, C514S254050, C514S365000

Reexamination Certificate

active

07074794

ABSTRACT:
The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products.The present inventors have found that derivatives having a substituent introduced into the γ-position of proline represented by the formula (I)wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.

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