Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 4 to 5 amino acid residues in defined sequence
Patent
1987-01-29
1989-02-14
Phillips, Delbert R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
4 to 5 amino acid residues in defined sequence
530331, 530338, C07K 706, C07K 510, A61K 3702
Patent
active
048047430
ABSTRACT:
This invention concerns novel renin-inhibitory peptides containing proline which are useful for treating renin associated hypertension and for treating hyperaldosteronism. Intermediates and processes for preparing both the intermediates and the novel peptides, pharmaceutical compositions, and methods of treatment are included. Also included is a method of diagnosis of renin-associated hypertension using the compounds of the invention.
REFERENCES:
patent: 4191753 (1980-03-01), Ryan
patent: 4384994 (1983-05-01), Veber et al.
patent: 4479941 (1984-10-01), Veber
patent: 4481192 (1984-11-01), Cazaubon et al.
patent: 4595677 (1986-06-01), Riniker et al.
patent: 4629724 (1986-12-01), Ryono et al.
patent: 4663310 (1987-05-01), Bock et al.
patent: 4668769 (1987-05-01), Hoover
patent: 4749687 (1988-06-01), Bindra
Kaltenbronn James S.
Lunney Elizabeth A.
Nicolaides Ernest D.
Anderson Elizabeth M.
Phillips Delbert R.
Warner-Lambert Copmany
Wessendorf T. D.
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