Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-12-10
2000-04-18
Schwartzman, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4352523, 43525233, 4353201, 536 231, 536 241, C12Q 168, C12N 121, C12N 1511, C12N 1570
Patent
active
060513810
ABSTRACT:
A two-hybrid system that can detect homo- and heterodimeric protein interactions in E. coli and other cells. This system is useful for the same applications as a yeast two-hybrid system; i.e. interaction cloning, mapping protein interaction domains, analyzing protein interactions, detecting protein interactions and detecting modulators thereof. The invention concerns a prokaryotic host cell comprising:
REFERENCES:
Jappelli et al. (1996) J. Mol. Biol. 259:575-8.
Marchetti et al (1995) J. Mol. Biol. 248:541-50.
Schmidt-Dorr et al. (1991) Biochem. 30:9657-64.
Dove et al. (1997) Nature 386:627-30.
Nakamura et al. (1972) J. Bacteriol. 110:329-35.
Higgins (1993) Curr. Opin. in Cell Biol. 5:684-687.
Allen et al. (1995) Trends in Biochem. Sci. 20:511-16.
Fields et al. (1989) Nature 340:245-6.
Liuzzi et al. (1994) nature 372:695-8.
Yan et al. (1995) Cancer Res. 55:3569-75.
Gibbs et al. (1994) Cell 79:193-198.
Luban et al. (1995) Curr. Opin. in Biotech. 6:59-64.
Fields et al. (1994) Trends Genet. 10:8:286-292.
Hollis et al. (1988) Proc. Natl. Acad. Sci. USA 85:5834-8.
Schleif (1996) in Echerichia coli and Salmonella Typhimurium Cellular and Mulecular Biology (Neidhardt, ed.) ASM Press, Washington, D.C. 1300-9.
Bustos & Schleif (1993) Proc. Natl. Acad. Sci. USA 90:5638-42.
Kim & Little (1992) Science 255:203-6.
Reeder & Schleif (1993) J. Mol. Biol. 231:205-218.
Elledge & Davis (1989) Genes & Dev. 3:185-197.
Mueller et al. (1996) J. Mol. Biol. 257:21-9.
Choy & Adhya (1992) Proc. Natl. Acad. Sci. USA 89:11264-8.
Huo et al. (1988) Proc. Natl. Acad. Sci. USA 85:5444-8.
Yang & Nash (1994) Proc. Natl. Acad. Sci 91:12183-12187.
Nash (1990) Trends Biochem. Sci. 15:222-7.
Pratt et al. (1996) Mol. Microbiol. 20:911-7.
Hoover et al. (1990) Cell 63:11-22.
Halazonetis et al. (1988) Cell 55:917-24.
Lee & Schleif (1989) Proc. Natl. Acad. Sci. 86:476-480.
Ryseck et al. (1990) Oncogene 5:1091-3.
Lewis et al. (1994) J. Miol. Biol. 241:507-23.
Golemis & Brent (1992) Mol. Cell Biol. 12:3006-14.
Huibregtse et al. (1991) EMBO J. 10:4129-35.
Rippe et al. (1995) Trends in Biochem. Sci. 20:500-06.
Wang & Giaever (1988) Science 240:300-06.
Nickerson & Achberger (1995) J. Bacteriol. 177:5756-61.
Chatterjee et al. (1997) Proc. Natl. Acad. Sci. USA 94:2957-62.
Giffard & Booth (1988) Mol. Gen. Genet. 241:148-152.
Muller & Sapp (1996) zirology 219:247-56.
Girling et al. (1993) Nature 352:83-87.
Kadesch (1993) Cell Growth & Different. 4:49-55.
Eustance et al. (1994) J. Mol. Biol. 242:330-338.
Cleland (1993) in Protein Folding: in Vivo and in Vitro, ed. J. Cleland (ACS) pp. 1-21.
Wall (1996) Bio Techniques 20:690-693.
Davis & Jacob (1968) J. Mol. Biol. 36:413-27.
Gaul Timothy J.
Schwartzman Robert A.
Sorrentino Joseph M.
LandOfFree
Prokaryotic two-hybrid system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Prokaryotic two-hybrid system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prokaryotic two-hybrid system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2335321