Prognostic tests for development of dermal stretch marks and...

Chemistry: analytical and immunological testing – Heterocyclic carbon compound – Hetero-o

Reexamination Certificate

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C436S086000, C435S005000, C435S006120

Reexamination Certificate

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07745225

ABSTRACT:
Various methods of assessing the regenerative potential of dermal tissue in a patient may be determined and methods to determine the potential development of stretch marks in a patient are provided. Through the analysis of a series of dermal tissue samples, a method of monitoring the aging process of the dermal tissue of a patient is possible. Damaged or stretched marked skin may also be used in the development of various diagnostic therapies relating to the inducement of the extracellular matrix components of the skin due to the loss of elastic fibers generally found in stretch marked skin.

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patent: 2005/0208150 (2005-09-01), Mitts et al.
patent: WO 01/07006 (2001-02-01), None
patent: WO 01/17486 (2001-03-01), None
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Lee, et al.;Decreased Expression of Collagen and Fibronectin Genes in Striase Distensae Tissue; Clinical and Experimental Dermatology; 1994; 19-285-288.
Watson, et al.;Fibrillin Microfibrils are Reduced in Skin Exhibiting Striae Distensae; British Journal of Dermatology; 1998; 138: 931-937.
Pierard, et al.;Tensile Properties of Relaxed Excised Skin Exhibiting Striae Distensae; Journal of Medical Engineering & Technology, vol. 23, No. 2, (Mar./Apr. 1989); pp. 69-72.
Kang, et al.;Topical Tretinoin(Retinoic Acid)Improves Early Stretch Marks; Arch Derm. vol. 132, May 1996; pp. 519-526.
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