Progesterone vaginal ring for treatment of infertility

Details Progesterone vaginal ring for treatment of infertility Progesterone vaginal ring for treatment of infertility

1996-06-28

1999-02-09

Saunders, David

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424430, 514177, 514805, 514899, 514964, 514967, 552502, A61F 608, A61K 3156, C07J 100

Patent

active

058690816

ABSTRACT:
The present invention relates to a method of administering progesterone to a normogonadal or a functionally agonadal human female undergoing an assisted reproduction technique. The invention further provides a method of hormone replacement for a human female. In a preferred embodiment of the present invention, progesterone is provided by intravaginal administration of a progesterone-containing polysiloxane ring.

REFERENCES:
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Diaz et al. (1985) Contraception 32:603.
Landgren et al. (1995) Contraception 45:343.
Landgren et al. (1995) Contraception 51:255.
Simon et al. (1986) Fertility and Sterility 46:619.
Ahren et al. (1983) Contraception 28:315.
Croxatto et al. "Progesterone vaginal rings for contraception during breastfeeding" in Female Contraception and Male Fertility Regulation, Runnebaum et al, eds. Parthenon Publishing, Casterton Hall, U.K., 1992, 135-142.
Diaz et al. (1985) Contraception 32:603.
Diaz et al. (1991) Ann. New York Acad. Sci. 626:11.
Matlin et al. (1992) Contraception 45:329.
Miles et al. (1994) Fertil. Steril. 62:485.
Sauer et al. (1987) Hum. Reprod. 2:287.
Smitz et al. (1992) Hum. Reprod. 7:168.
Victor et al. (1978) Fertil. Steril. 30:631.
WHO Special Programme of Research, Development and Research Training in Human Reproduction (1979) J. Steroid Biochem. 11:461.

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