Products displaying the antigenicity of hepatitis B virus e anti

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 7, 435 68, 435810, 436543, 530403, 530412, 530806, 530810, 530825, 530826, C07K 100, C07K 300, G01N 33563, G01N 33576

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047585072

ABSTRACT:
Polypeptides displaying the antigenicity of hepatitis B virus e antigens, DNA sequences coding for those polypeptides, antibodies to those polypeptides and methods of producing and using those polypeptides, antibodies and DNA sequences. The polypeptides and antibodies of this invention are characterized by their use in compositions and methods for detecting hepatitis B virus infective carriers and in evaluating the course of HBV-related active liver disease.

REFERENCES:
patent: 3636191 (1972-01-01), Blumberg et al.
patent: 4017360 (1977-04-01), Bertland et al.
patent: 4021540 (1977-05-01), Pollack et al.
patent: 4102996 (1978-07-01), McAleer et al.
patent: 4118479 (1978-10-01), Prince et al.
patent: 4138287 (1979-02-01), Andersson et al.
patent: 4162192 (1979-07-01), Mizuno et al.
patent: 4164565 (1979-11-01), Prince et al.
patent: 4164566 (1979-11-01), Provost et al.
patent: 4197361 (1980-04-01), Hoff et al.
patent: 4204989 (1980-05-01), McAleer et al.
patent: 4234564 (1980-11-01), McAleer
patent: 4301250 (1981-11-01), Marks et al.
patent: 4617260 (1986-10-01), McAleer
A. M. Maxam & W. Gilbert, "Sequencing En-Labeled DNA with Base-Specific Chemical Cleavages", Methods Enzymol., 65, pp. 499-560 (1980).
O. Ouchterlony, in Progress in Allergy, P. Kallos & R. Waksman (Eds.), Karger, New York, 5, pp. 1-78 (1958).
Maxam, A. M. et al., Proc. Natl. Acad. Sci. USA, 74 (2), 560-564 (1977).
"Handbook of Experimental Immunology", D. M. Weir, Ed., Chapter 19 by O. Ouchterlony, pp. 655-706, Blackwell, Oxford, England, 1967.
V. D. Waart, M. et al., J. Med. Virol., 3(1), 43-49 (1978).
Katz, D. et al., J. Med. Virol., 5(1), 87-100 (1980).
Chemical Abstracts, I, 93:5802t (1980).
Chemical Abstracts, II, 97:160725w (1982).
Chemical Abstrats, III, 102:172627a (1985).
H. Boyer and D. Roulland-Dussoix, "A Complementation Analysis of the Restriction and Modification of DNA in Escherichia Coli", J. Mol. Biol., 41, pp. 459-472 (1969).
S. Broome and W. Gilbert, "Immunological Screening Method to Detect Specific Translation Products", Proc. Natl. Acad. Sci. USA, 75, pp. 2746-2749 (Jun. 1978).
A. Budkowska et al., "Identification of Two HBeAg Subspecificities Revealed by Chemical Treatment and Enzymatic Digestion of Liver-Derived HBcAg", J. Immunol., 123, pp. 1415-1416 (1979), [Budkowska et al. I].
A. Budkowska et al., "Immunochemistry and Polypeptide Composition of Hepatitis B Core Antigen (HBcAg)", J. Immunol., 118, pp. 1300-1305 (1977), [Budkowska et al. II].
C. J. Burrell et al., "Expression in Escherichia Coli of Hepatitis B Virus DNA Sequences Cloned in Plasmid pBR322", Nature, 279, pp. 43-47 (May 1979).
P. Charnay et al., "Cloning in Escherichia Coli and Physical Structure of Hepatitis B Virion DNA", Proc. Natl. Acad. Sci. USA, 76, pp. 2222-2226 (1979).
D. Clewell, "Nature of Col E.sub.1 Plasmid Replication in Escherichia Coli in the Prsence of Chlorampheicol", J. Bacteriol, 110, pp. 667-676 (1972).
B. J. Cohen & Y. E. Cossart, "Application of A Screening Test for Antibody to Hepatitis B Core Antigen", J. Clin. Path., 30, pp. 709-713 (1977).
D. S. Dane et al., "Virus-Like Particles in Serum of Patients with Australian-Antigen-Associated Hepatitis", The Lancet, pp. 695-698, ( Apr. 4, 1970).
J. Edman et al., "Synthesis of Hepatitis B Surface and Core Antigens in E. Coli", Nature, 291, pp. 503-506 (1981).
H. A. Fields et al., "Purification and Partial Characterization of Hepatitis e Antigen", Infection & Immunity, 20, pp. 792-803 (1978).
A. Fritsch et al., "Cloning of the Genome of Hepatitis B Virus in Escherichia Coli", C. R. Acad. Sc. Paris, t. 287, Ser. D., pp. 1453-1456. (Dec. 18, 1978)--translation included.
F. Galibert et al., "Nucleotide Sequence of the Hepatis B Virus Genome (Subtype ayw) Cloned in E Coli", Nature, 281, pp. 646-650 (Oct. 25, 1979).
T. A. Landers et al., "Structure of Hepatitis B Dane Particle DNA and Nature o the Endogenous DNA Polymerase Reaction", J. Virology, 23, pp. 368-376. (Aug. 1977).
L. I. Lutwick & W. S. Robinson , "DNA Synthesized in the Hepatitis B Dane Particle DNA Polymerase Reaction", J. Virology, 21, pp. 96-104 (Ja. 1977).
P. MacKay et al., "The Conversion of Hepatitis B Core Antigen Synthesized in E. Coli into e Antigen", J. Med. Virol., 8, pp. 237-243 (1981).
L. Magnius et al., "A New Antigen-Antibody System", J. Amer. Med. Assoc., 231, pp. 356-359, (1975).
L. Magnius & J. Espmark, "New Specificities in Australia Antigen Positive Sera Distinct from the LeBuvier Determinants", J. Immunol., 109, pp. 1017-1021 (1972).
M. Mandel & A. Higa, "Calcium-Dependent Bacteriophage DNA Infection", J. Mol. Biol., 53, pp. 159-162 (1970).
J. L. Melnick et al., "Approaching the Control of Viral Hepatitis Type B", J. Infectious Diseases, 133, pp. 210-225 (1976).
A. R. Neurath et al., J. Genl Virol., 30, pp. 277-285 (1976).
A. R. Neurath & N. Strick, "Host Specificity of a Serum Marker for Hepatitis B: Evidenc that e Antigen has the Properties of an Immunogloublin", Proc. Natl. Acad. Sci. USA, 74, pp. 1702-1706 (1977).
H. Ohori et al., "Antigenic Conversion from HBcAg to HBeAg by Degradaton of Hepatitis B Core Particles", Interviroloyg, 13, pp. 74-82 (1980).
M. Pasek et al., "Hepatitis B Virus Genes and Their Expression in E. Coli", Nature, 282, pp. 575-579 (Dec. 6, 1979).
B. G. Werner et al., "_Association of e Antigen with Dane _Particle DNA in Sera from _Asymptomatic Carriers of Hepatitis B Surface _Antigen", Proc. Natl. Acad. _Sci. USA, 74, pp. 2149-2151 _(May 1977).
H. Yoshizawa et al., "_Demonstration of Hepatitis B e Antigen _in Hepatitis B Core Particles Obtained _from the Nucleus of Hepatocytes Infected with _Hepatitis B Virus," J. Gen. Virol., 42, pp. 513-519 (1979).
W. S. Robinson, "The Genome of Hepatitis B Virus", Ann. Rev. Microbiol., 31, pp. 357-377 (1977).
J. J. Sninsky et al., "Cloning and Endonuclease Mapping of the Hepatitis B Viral Genome", Nature 279, pp. 346-348 (May 24, 1979).
S. Stahl et al., "Hepatitis B Virus Core Antigen, Its Synthesis in Escherichia coli and Application in Diagnosis", Proc. Natl. Acad. Sci. USA, 79, pp. 1606-1610 (1981).
J. Summers et al., "Genome of Hepatitis B Virus: Restriction Enzyme Cleavage and Structure of DNA Extracted from Dane Particles", Proc. Natl. Acad. Sci. USA, 72, pp. 4597-4601 (Nov. 1975).
K. Takahashi et al., "Association of Dane Particles with e Antigen in the Serum of Asymptomatic Carriers of Hepatitis B Surface Antigen", J. Immunol., 117, pp. 102-105 (1976).
K. Takahashi et al., "Demonstration of Hepatitis B e Antigen in the Core of Dane Particles", J. Immunol., 122, pp. 275-279 (1979).
K. Takahashi et al., Hepatitis B e Antigen Polypeptides Isolated from Sera of Individuals Infected with Hepatitis B Virus: Comparison with HBeAg Polypeptide Derived from Dane Particles", J. Gen. Virol., 50, pp. 49-57 (1980) [Chem. Abstracts 94: 63509; (1981)].
P. Valenzuela et al. "Nucleotide Sequence of the Gene Coding for the Major Protein of Hepatitis B Virus Surface Antigen", Nature 280, pp. 815-819 (Aug. 30, 1979).
G. N. Vyas et al., "Hepatitis B Virus `e` Antigen: An Apparent Association With Lactate Dehydrogenase Isoenzyme-5", Science, 198, pp. 1068-1070 (1977).

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