Products and methods for controlling the suppression of the neop

Details Products and methods for controlling the suppression of the neop Products and methods for controlling the suppression of the neop

1994-11-14

1999-01-12

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Vector, per se

536 231, C12N 1500

Patent

active

058587713

ABSTRACT:
A method for gene therapy for cancers wherein chromosomal location of an inactive or defective cancer suppressing gene is established, a replacement gene which is preferably cloned is then used to replace the inactive or defective cancer suppressing gene in the chromosome. In addition to its uses in therapy, the present invention provides a means for prophylactically treating individuals having a genetic predisposition to cancer and provides an animal model for testing for carcinogenicity of environmental substances.

REFERENCES:
patent: 4497796 (1985-02-01), Salser et al.
patent: 5532220 (1996-07-01), Lee et al.
Friedman, Cancer Supp. 70(6) : 1807-1817 (1992).
Angier, N., Discover Mar.:85-96 (1987).
Benedict et al., Cancer Genet. and Cytogenet. 10:311-333 (1983).
Benedict et al., Science 219:973-975 (1983).
Bender et al., J. Mol. Biol. 168:17-33 (1983).
Bookstein et al., Proc. Natl. Acad. Sci. USA 85:2210-2214 (1988).
Bookstein et al., Science 247:712-715 (1990).
Cavenee et al., Am. J. Hum. Genet. 36:10-24 (1984).
Cavenee et al., Nature 305:770-784 (1983).
Cepko et al., Cell 37:1053-1062 (1984).
Dryja et al., Proc. Natl. Acad. Sci. USA 83:7391-7394 (1986).
Friend et al., Nature 323:643-646 (1986).
Friend et al., Proc. Natl. Acad. Sci USA 84:9059-9063 (1987).
Fung et al., Science 236:1657-1661 (1987).
Gossler et al., Proc. Natl. Acad. Sci. USA 83:9065-9069 (1986).
Harris, Henry, Nature 323:582-583 (1986).
Hooper et al., Nature 326:292-295 (1987).
Kantoff et al., Proc. Natl. Acad. Sci. USA 83:6563-6567 (1986).
Kuehn et al., Nature 326:295-298 (1987).
Lee et al., Nature 329:642-645 (1987).
Lee et al., Proc. Natl. Acad. Sci. USA 83:6337-6341 (1986).
Lee et al., Proc. Natl. Acad. Sci. USA 83:6790-6794 (1986).
Lee et al., Proc. Natl. Acad. Sci. USA 85:6017-6021 (1988).
Lee et al., Science 235:1394-1399 (1987).
Lee et al., Science 241:218-221 (1988).
Mann et al., Cell 33:153-159 (1983).
Miller et al., Molecular and Cellular Biol. 5(3): 431-437 (1985).
Miller et al., Proc. Natl. Acad. Sci. USA 80:4709-4713 (1983).
Miller et al., Cold Spring Harbor Symposia on Quantitative Biology LI:1013-1019 (1986).
Murphree et al., Science 223:1028-1033 (1984).
Shew et al., Oncogene Research 1:205-214 (1989).
Strong et al., Science 213:1501-1503 (1981).
Thomas et al., Cell 44:419-428 (1986).
Weissman et al., Science 236:175-180 (1987).
Vieweg et al. "Considerations for the Use of Cytokine-Secreting Tumor Cell Preparations for Cancer Treatment," Cancer Investigation, vol. 13 (2):192-201, 1995.
Vieweg et al. "Immunotherapy of Prostate Cancer in the Dunning Rat Model: Use of Cytokine Gene Modified Tumor Vaccines," Cancer Research, vol. 54:1760-1765, Apr. 1994.
Miller, A.D. "Progress Toward Human Gene Therapy," Blood, vol. 76(2):271-278, Jul. 1990.
Roemer et al. "Concepts and strategies for human gene therapy," Eur. J. Biochem., vol. 208:211-225, 1992.

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