Plastic and nonmetallic article shaping or treating: processes – Formation of solid particulate material directly from molten...
Patent
1999-05-05
2000-11-28
Mullis, Jeffrey C.
Plastic and nonmetallic article shaping or treating: processes
Formation of solid particulate material directly from molten...
264 13, B29B 902
Patent
active
061531294
ABSTRACT:
The present invention relates to a method for forming microparticles of a material from microdroplets of a solution, wherein the solution comprises the material dissolved in a solvent. The method includes the steps of directing the microdroplets into a freezing zone, wherein the freezing zone is surrounded by a liquified gas, and wherein the microdroplets freeze. The frozen microdroplets are then mixed with a liquid non-solvent, whereby the solvent is extracted into the non-solvent, thereby forming the microparticles.
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Healy Michael S.
Herbert Paul F.
Alkermes Controlled Therapeutics Inc.
Mullis Jeffrey C.
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