Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Patent
1989-12-14
1993-03-16
Nucker, Christine M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
530350, C07K 300, A61K 3736
Patent
active
051945967
ABSTRACT:
There is described an isolated vascular endothelial cell growth factor selected from the group consisting of bovine vascular endothelial cell growth factor of 120 amino acids and human vascular endothelial cell growth factor of 121 amino acids. The vascular endothelial cell growth factor is useful in the treatment of wounds in which neovascularization or reendothelialization is required for healing.
REFERENCES:
Leung et al Science vol. 246: 1306-1309, Dec. 9, 1989, "Vascular Endothelial Growth Factor is a Secreted Angiogenic Mitogen".
Abraham Judith A.
Fiddes John C.
Mitchell Richard L.
Tischer Edmund G.
California Biotechnology Inc.
Nucker Christine M.
Shearer Peter R.
Sidberry H. F.
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