Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2000-06-20
2008-11-18
Duffy, Patricia A (Department: 1645)
Chemistry: molecular biology and microbiology
Vector, per se
C435S252300
Reexamination Certificate
active
07452715
ABSTRACT:
The expression of the lipidated form of the peptidoglycan-associated protein (PAL) of gram-negative bacteria is achieved through the use of a plasmid containing a tightly regulated promoter. A bacterial host cell is transformed, transduced or transfected with such a plasmid. The host cell is then cultured under conditions such that the lipidated recombinant PAL is expressed. The lipidated recombinant PAL is included in an antigenic composition administered to a mammalian host to immunize against a gram-negative bacterium.
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Duffy Patricia A
Gordon Alan
Moran Michael
Silver Joel B.
Wyeth Holdings Corporation
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