Production of sustained released system

Plastic and nonmetallic article shaping or treating: processes – Encapsulating normally liquid material – Liquid encapsulation utilizing an emulsion or dispersion to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

71 6411, 71DIG1, 264 43, 424424, 424425, 424493, 424497, 426 89, 426103, 514963, 6048921, A61K 962, A61K 964, B01J 1302

Patent

active

047895160

ABSTRACT:
Permeable capsules are loaded with a reservoir of the substance to be dispensed at a concentration sufficient to provide an osmotic pressure above threshold level, and the pore size of the capsule membrane is controlled so that the passage of the substance through the membrane becomes the rate-limiting factor in dispensing. Shape-retaining spheres are formed from a water-soluble polymer containing plural anionic or cationic groups and cross-linking surface layers of the spheres by contact with a polymer having plural groups of charge opposite that of the water-soluble polymer. After loading, the capsules are again treated with the same or a different cross-linking polymer to reduce the dimensions of the pores.

REFERENCES:
patent: 3464413 (1967-05-01), Goldfarb et al.
patent: 3474777 (1969-10-01), Figge
patent: 3516943 (1970-06-01), Brynko et al.
patent: 3520821 (1970-07-01), Striley et al.
patent: 3645911 (1972-02-01), van Besauw et al.
patent: 3921632 (1975-11-01), Bardani
patent: 3937668 (1976-02-01), Zolle
patent: 3948263 (1976-04-01), Drake, Jr. et al.
patent: 3993073 (1976-11-01), Zaffaroni
patent: 3994827 (1976-11-01), Sakai et al.
patent: 4067961 (1978-01-01), Laughlin
patent: 4205060 (1980-05-01), Monsimer et al.
patent: 4221778 (1980-09-01), Raghunathan
patent: 4251387 (1981-02-01), Lim et al.
patent: 4322311 (1982-03-01), Lim et al.
patent: 4324683 (1982-03-01), Lim et al.
patent: 4352883 (1982-10-01), Lim
patent: 4407957 (1983-10-01), Lim
patent: 4459279 (1984-07-01), Stricker et al.
patent: 4475916 (1984-10-01), Himmelstein
patent: 4478596 (1984-10-01), Michelson
Controlled-Release Drug Delivery and Pennkinetic.
Pennwalt Corp. Prescription Division-(1983) Pennwalt Pharmaceutical Division.
Lim and Moss (1981) J: Pharm. Sci. 70: 351-354.
Lim and Sun (1980) Science 210: 908-910.
Leung et al. (1983) Artificial Organs 7: 208-212.
"Science and Technology Brief" (1983) The Economist, Apr 9th pp 80-81.
Patent Abstracts of Japan, unexamined applications, Section C 1 (48), May 11 , 1977 p. 7, c77 Kolai No. 52-3 890.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Production of sustained released system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Production of sustained released system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of sustained released system will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1493016

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.