Production of specific immune nucleic acids cell dialysates and

Details Production of specific immune nucleic acids cell dialysates and Production of specific immune nucleic acids cell dialysates and

1977-12-14

1980-09-23

Waddell, Frederick E.

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

A01N 102

Patent

active

042244048

ABSTRACT:
Gamma-globulins and immune nucleic acids, both specific to a given antigen, are produced by culturing in vitro an inducible cell line in the presence of specific immune nucleic acids or specific immune dialysates obtained either from human or animal donor lymphoid cells sensitized to said specific antigen or from cells of a previously induced cell line sensitized to said specific antigen, or in the presence of the liquid phase of a culture of a previously induced cell line sensitized to said specific antigen; and extracting gamma-globulins from the liquid phase of the thus induced cell culture and/or extracting the immune nucleic acids from the cells so cultured. Specific immune dialysates may also be produced by a similar process.

REFERENCES:
Moore et al.-J.A.M.A. vol. 199, No. 8, Feb. 20, 1967, pp. 87-92.
Baumal et al.-Nature vol. 230, 1971, pp. 20 & 21.
Nilsson et al.-Int. J. Cancer vol. 8, (1971), pp. 443-450.
Paltrowitz et al.-Mt. Sinai J. vol. 38, (1971), pp. 284-292.
Willmer--Cells and Tissues in Culture, (1966), vol. 3, pp. 330-334.

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