Production of sophorolipid acetate acids from oils or esters

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435124, 435134, 435137, 435171, 435 72, 435249, 4352554, C12P 1712, C12P 1702

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059003669

ABSTRACT:
A process for the fed batch production of a sophorolipid composition is described, in which culturing takes place of at least one Candida bombicola strain in a culture medium incorporating a sugar and a nitrogen source and said cultured strain is exposed in a reaction zone to a supply of an appropriate substrate under adequate aeration, temperature and pH conditions and at least once the following sequence is performed: a) the strain is continuously supplied with substrate at a supply rate in the reaction zone between 0.01 and 4 grams per hour and per liter of initial reaction volume and for a supply time such that the residual substrate concentration in the reaction zone is maintained at a value at the most equal to 18 grams per liter of initial reaction volume during said supply time; and b) the sophorolipid composition produced is recovered; the process being characterized in that the substrate essentially consists of at least one animal oil, at least one vegetable and/or at least one ester of said oil, said oils and said ester incorporating an aliphatic linear chain with 10 to 24 carbon atoms.

REFERENCES:
patent: 3205150 (1965-09-01), Spencer et al.
patent: 3312684 (1967-04-01), Spencer et al.
patent: 3445337 (1969-05-01), Spencer et al.
patent: 3622344 (1971-11-01), Allingham
patent: 4753885 (1988-06-01), Dietsche et al.
Hans-Joachim Asmer et al., "Microbial Production, Structure Elucidation, and Bioconversion of Sophorose Lipids," Journal of the American Oil Chemists'Society, vol. 65, No. 9, Sep. 1988, pp. 1460-1466.

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