Production of selenium-72 and arsenic-72

Details Production of selenium-72 and arsenic-72 Production of selenium-72 and arsenic-72

1991-09-06

1993-04-20

Walsh, Donald P.

Chemistry of inorganic compounds

Treating mixture to obtain metal containing compound

Radioactive metal

423 87, 423508, 423510, 210759, 376156, 203 5, 156DIG72, 156DIG81, C01G 5700, C01G 2800

Patent

active

052040720

ABSTRACT:
Methods for producing selenium-72, separating it from its daughter isotope arsenic-72, and generating multiple portions of a solution containing arsenic-72 from a reusable parent substance comprised of selenium-72.

REFERENCES:
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patent: 4411698 (1983-10-01), Badasha
patent: 4615731 (1986-10-01), Thomas et al.
patent: 4663141 (1987-05-01), Sonoda et al.
S. H. Al-Kouraishi et al. "An Isotope Generator for .sup.72 AS," Int. J. of Applied Radiation and Isotopes, vol. 29, pp. 607-609 (1978).
Daniela Basile et al., "Excitation Functions and Production of Arsenic Radioisotopes for Environmental Toxicology and Biomedical Purposes," Int. J. of Applied Radiation and Isotopes, vol. 32, pp. 403-410 (1981).
Patrick M. Grant et al., "Medium-Energy Spallation Cross Sections. 1. RbBr Irradiation with 800-MeV Protons," Int. J. of Applied Radiation and Isotopes, vol. 33, pp. 415-417 (1982).
Ragnar Bye, "Critical Examination of Some Common Reagents for Reducing Selenium Species in Chemical Analysis," Talanta, vol. 30, No. 12, pp. 993-996 (1983).
Regin Weinreich et al., "Production of .sup.72 Se/.sup.72 AS and .sup.73 Se by Medium Energy Protons," J. of Labelled Compounds and Radiopharmaceuticals, pp. 146-147 (1990).
Anthony L. Fellu, "The Role of Chemistry in Positron Emission Tomography," Department of Neurology, Memorial Sloan-Kettering Cancer Center, vol. 65, No. 8, pp. 655-660 (1988).
D. R. Phillips et al., "Chemistry and Concept for an Automated Se-72/As-72 Generator," Los Alamos National Laboratory LA-UR-91-517, submitted to New Trends in Radiopharmacuetical Synthesis, Quality Assurance and Regulatory Control, Plenum Publishing Corporation, New York, 1991.
Dennis R. Phillips et al., "Electrolytic Separation of Selenium Isotopes from Proton Irradiated RbBr Targets," Appl. Radiat. Isot., vol. 38, No. 7, pp. 521-525 (1987).

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