Production of recombinant protein pap 31 for the diagnosis...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C435S005000

Reexamination Certificate

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11239444

ABSTRACT:
The invention relates to a recombinant DNA and polypeptide sequence of an immuno-dominant phage particle associated protein fromBartonella bacilliformis. The recombinant protein is easily produced permitting the conduct of more accurate and rapid diagnositic assays for the detection ofB. bacilliformisinfection with reduced reagent and equipment requirements over that required by currently available methods of diagnosis. The DNA and polypeptide sequence is also useful in vaccine preparations againstB. bacilliformis.

REFERENCES:
Bowers et al., Gene 206:49-52, 1998.
Greenspan et al. (Nature Biotechnology 7: 936-937, 1999.
Klein, Immunology, the Science of Self-Nonself Discrimination, John Wiley & Sons, 1982.

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