Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-09-11
1998-10-13
Knode, Marian C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 5, 4352351, 4352542, 4241861, 4242041, 4241301, 5303731, 536 2372, 935 65, 935 61, C12Q 170, C12P 2106, A61K 3921, A61K 3912
Patent
active
058210873
ABSTRACT:
The present invention is directed to a recombinant human papillomavirus type 11 L1 protein encoded by a synthetic DNA molecule and methods of making and using the protein.
REFERENCES:
patent: 5437951 (1995-08-01), Lowy et al.
Browne, et al., "Analysis of the L1 Gene Product of Human Papillomavirus Type 16 by Expression in a Vaccinia Virus Recombinant" J. Gen. Virol. (1988) vol. 69, pp. 1263-1273.
Doorbar, et al., "Identification of Proteins Encoded by the L1 and L2 Open Reading Frames of Human Papillomavirus 1a", J. of Virol., Sep. 1987, vol. 67, No. 9., pp. 2793-2799.
Hanenese, et al., "Self-Assembly of Human Papillomavirus Type 1 Capsids by Expression of the L2 Protein Alone or by Coexpression . . . ", J. of Virol., Jan. 1993, vol. 67, No. 1, pp. 315-322.
Kirnbauer, R., "Papillomavirus L1 Major Capsid Protein Self-assembles into Virus-like Particles that are Highly Immunogenic", Proc. Natl. Acad. Sci., vol. 89, pp. 12180-12184, Dec. 1992.
LeCann, et al., "Self-Assembly of Human Papillomavirus Type 16 Capsids by Expression of the L1 Protein in Insect Cells", FEMS Microb. Lett., 117 (1994), pp. 269-274.
Lin, et al., "Effective Vaccination Against Papilloma Development by Immunication with L1 or L2 Structural Protein . . . ", Virology, vol. 187, (1992) pp. 612-619.
Rose, et al., "Expression of Human Papillomavirus Type 11 L1 Protein in Insect Cells: In Vivo and In Vitro Assembly of Viruslike Particles", J. of Virol., Apr. 1993, pp. 1936-1944.
Steele, et al., "Humoral Assays of Human Sera to Disrupted and Nondisrupted Epitopes of Human Papillomavirus Type 1", Virology, vol. 174, (1990) pp. 388-398.
Strike, et al., "Expression in Escherichia Coli of Seven DNA Fragments Comprising the Complete L1 and L2 Open . . . ", J. Gen. Virol. (1989) vol. 70, pp. 543-555.
Zhou, et al., "Synthesis and Assembly of Infectious Bovine Papillomavirus Particles in Bitro", J. Gen. Virol., (1993), Fol. 74, pp. 763-768.
Zhou, et al., "Expression of Vaccinia Recombinant HPV HPV 16 L1 and L2 ORF Proteins in Eipthelial Cells . . . ", Virology, vol. 185, (1991), pp. 251-257.
Zhou, et al., "Increased Antibody Responses to Human Papillomavirus Type 16 L1 Protein Expressed by Recombinant Vaccinia . . . ", J. Gen. Virology, (1990), vol. 71, pp. 2185-2190.
Sasagawa, et al., "Synthesis and Assembly of Virus-like Particles of Human Papillomaviruses Type 6 . . . ", Virology, 206, pp. 126-135 (1995).
Rose et al. 1993, J. of Virology, vol. 67 (4), pp. 1936-1944.
George Hugh A.
Hofmann Kathryn J.
Jansen Kathrin U.
Joyce Joseph G.
Lehman E. Dale
Giesser Joanne M.
Knode Marian C.
Merck & Co. , Inc.
Salimi Ali R.
Tribble Jack L.
LandOfFree
Production of recombinant human papillomavirus type II protein u does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production of recombinant human papillomavirus type II protein u, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of recombinant human papillomavirus type II protein u will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-312443