Production of recombinant human lactoferrin

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Metal containing – e.g. – chromoproteins – ferritin,...

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530395, 530412, 435 691, 435 697, 43525911, 4352542, 43525421, 43525423, 4352543, 4353201, 536 234, 536 235, 536 241, 935 10, 935 27, 935 28, 935 37, 935 48, 935 68, 935 69, C07K 1479, C12N 1512, C12N 1562, C12N 1580

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055718965

ABSTRACT:
The present invention provides novel plasmids, transfected eucaryotic cells and methods of producing these plasmids and transfected eucaryotic cells. The novel plasmid contains the cDNA for human lactoferrin protein. Methods for the production of human lactoferrin protein in A. Oryzae are also provided. Thus, the present invention provides an efficient and economical means for the production of recombinant human lactoferrin protein.

REFERENCES:
patent: 4652639 (1987-03-01), Stabinsky
patent: 4740461 (1988-04-01), Kaufman
patent: 5155037 (1992-10-01), Summers
patent: 5304633 (1994-04-01), Tomita et al.
Epstein, J. B., et al., Reviews of Infectious Diseases, vol. 6, No. 1, "Oral Candidiasis: Pathogenesis and Host Defense", pp. 96-106. 1984.
Soukka, T., et al., FEMS Microbiology Letters, vol. 90, "Fungicidal effect of human lactoferrin against Candida albicans", pp. 223-228 (1992).
M. Metz-Boutigue et al. "Human lactotransferrin: amino sequence and structural comparisons with other transferrins" Eur. J. Bioch., 145:659-676 (1984).
B. Anderson et al.; "Structure of Human Lactoferrin: Crystallographic Structure Analysis and Refinement at 1-8 A Resolution" J. Mol. Biol. 209:711-734 (1989).
K. Stowell et al.; "Expression of cloned human lactoferrin in baby-hamster kidney cells" Biochem. J., 276:349-355 (1991).
P. Mead et al.; "cDNA and protein sequence of bovine lactoferrin" Nucleic Acids Research, 18:7167, No. 18 (1990).
M. Rey et al.; "Complete nucleotide sequence of human mammary gland lactoferrin", 18:5288, No. 17 (1990).
M. Powell et al.; "Nucleotide sequence of human lactoferrin cDNA" Nucleic Acids Research, 18:4013, No. 13 (1990).
B. Pentecost et al.; "Lactotransferrin Is the Major Estrogen Inducible Protein of Mouse Uterine Secretions" J. Biological Chem., 262:10134-10139, No. 21 (1987).
T. Rado et al.; "Isolation of Lactoferrin cDNA From a Human Myeloid Library and Expressions of mRNA During Normal and Leukemic Myelopoiesis" Blood, 70:989-993, No. 4 (1987).
A. Pierce et al.; "Molecular cloning and sequence analysis of bovine lactotransferrin" Eur. J. Biochem., 196:177-184 (1991).
Valenti et al. 1986, FEMS Microbiology Letters 33:271-275.
Promego, 1988/89, Price List, 2800 S. Fish Hatchery Road, Madison, WI.
Huge-Jensen et al. 1989. Lipids, 24(9): 781-785.
Siner et al. 1989. Gene, 79:107-117.
von Heyne, G. 1984, J. Mol. Biol. 173:243-251.

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