Production of radioiodinated T.sub.3 and T.sub.4

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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23230B, 232303, A61K 4300, G21H 502

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active

041928580

ABSTRACT:
The chloramine T procedure is employed to provide radioiodinated T.sub.3 and radioiodinated T.sub.4 from T.sub.3 and T.sub.4, respectively, at specified pHs and mole ratios to provide for long shelf life. T.sub.3 is also radioiodinated to high specific activity radioiodinated T.sub.4, and purified after a specified waiting period to remove radioactive non-antigenic contaminants and thereby provide a long shelf life.

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Latham et al., J. Biol. Chem., 251, 7388 (1976).
Jiang et al., J. Am. Chem. Soc., 97, 6551 (1975).

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