Production of quinic acid derivatives

Details Production of quinic acid derivatives Production of quinic acid derivatives

1993-07-21

1995-03-07

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

562508, 549362, C07D30700

Patent

active

053959507

ABSTRACT:
1-, 5-O-mono- and 3,4-0-bis-substituted derivatives of quinic acid are prepared by reacting a derivative of a hydroxycinnamic acid of which the hydroxyl group(s) is/are protected with a quinic acid derivative to form an ester and the protective groups are then cleaved under controlled conditions of acidity and temperature. These conditions provide for regiospecificity of the esterification and enable any degradation of isomerization to be avoided. The process gives new quinides in high yields.

REFERENCES:
patent: 3855297 (1974-12-01), Diana et al.
patent: 4818767 (1989-04-01), Rossignal
patent: 4940803 (1990-07-01), Mills et al.
Ichikawa, et al., Chemical Abstracts, vol. 116, No. 23, No. 236095z (1992).
Wynne et al CA 106(9) 64477a 1986.
Haslam, et al., "Synthesis and Properties of Some Hydboxycinnamoyl Esters of Quinic Acid," J. Chem. Soc. pp. 2137-2146 (1964).

Affiliated with

Also associated with

Rating

Production of quinic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Production of quinic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of quinic acid derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1407085