Production of purified porcine immunoglobulins

Details Production of purified porcine immunoglobulins Production of purified porcine immunoglobulins

1985-06-25

1986-11-18

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Lymphokine

426647, 426580, 426588, 426657, 530387, 530360, 530365, 530832, 530833, A61K 3516, A61K 39395

Patent

active

046235418

ABSTRACT:
A method for the continuous production of a purified immunoglobulin preparation wherein the antibodies are substantially enriched by means of a selective two-step ammonium sulfate fractionation procedure employing centrifugation and ion depletion processes. The purified immunoglobulins are subsequently commingled with condensed skim milk and spray dried. The resulting product for example is employed in the formulation of milk replacers for artificial rearing of neonatal pigs to provide the passive immunity to disease normally provided by sows' colostrum and later milk.

REFERENCES:
patent: 3984539 (1976-10-01), Khouw et al.
patent: 4096244 (1978-06-01), Newson et al.
patent: 4276283 (1981-06-01), Eibl et al.
McCallum et al, Can. J. Animal Sci. 57, 151-158 (1978).

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