Production of pulverulent mixtures of lipidic and hydrophobic co

Details Production of pulverulent mixtures of lipidic and hydrophobic co Production of pulverulent mixtures of lipidic and hydrophobic co

1983-02-10

1985-04-02

Padgett, Ben R.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

4284022, 264 46, 436829, 424 64, 424 69, 424 94, 424 95, B01J 1300, A61K 942

Patent

active

045087032

ABSTRACT:
The invention relates to a method for preparing a pulverulent mixture of amphiphilic lipidic constituents and possibly of hydrophobic constituents, as well as to a method for producing hydrated lipidic lamellar phases from the pulverulent mixture.
The method comprises dissolving the amphiphilic lipidic constituents and the hydrophobic constituents in an appropriate solvent and then atomizing said solution in a flow of gaseous fluid to produce the pulverulent mixture. The mixture thus obtained is a homogeneous and very fine powder which can be very easily dispersed in a suitable aqueous dispersion medium to produce either slightly hydrated lipidic lamellar phases or highly hydrated lipidic lamellar phases such as liposomes useful in the pharmaceutical and cosmetic fields.

REFERENCES:
patent: 3207666 (1965-09-01), Houtgraaf et al.
patent: 3499962 (1970-03-01), Wurzburg et al.
patent: 4235792 (1980-11-01), Hsia et al.

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