Production of proteins by autoproteolytic cleavage

Details Production of proteins by autoproteolytic cleavage Production of proteins by autoproteolytic cleavage

2008-05-27

2008-05-27

Nashed, Nashaat T. (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S069700, C435S212000, C435S252310, C435S320100, C536S023200

Reexamination Certificate

active

07378512

ABSTRACT:
The present invention relates to a process for the production of a heterologous polypeptide with homogeneous N-terminus in a bacterial host cell, wherein the heterologous polypeptide is autoproteolytically cleaved from an expressed fusion protein which comprises a polypeptide with the autoproteolytic activity of an autoprotease Nproof a pestivirus and the heterologous polypeptide by the Nproautoproteolytic activity.

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