Production of protein with reduced nucleic acid

Details Production of protein with reduced nucleic acid Production of protein with reduced nucleic acid

1980-10-24

1982-07-27

Warden, Robert J.

Food or edible material: processes, compositions, and products

Fermentation processes

Of or with yeast or mold

260112R, 426 61, 426 62, 426656, 435270, 435804, A23L 128

Patent

active

043418023

ABSTRACT:
Microorganisms with low nucleic acid content are produced by acid treating of the microorganism. One embodiment relates to the extraction of so treated microorganisms after their separation from the acid treating fluid, using a strong base for the extraction. Another embodiment relates to the neutralization of the acid treating fluid containing nucleic acids prior to the introduction of this fluid into the fermentation zone, the anion of the acid and the metal cation used in the neutralization step forming minerals desirable for the growth medium in the fermentation step.

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patent: 4007088 (1977-02-01), Fencl et al.
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patent: 4133904 (1979-01-01), Steer et al.
Miguel A. Otero et al., Biotechnology Letters, vol. 2, No. 9, pp. 379-384, 1980.
L. Viikari and M. Linko, Process Biochemistry, vol. 12, No. 4, Reduction of Nucleic Acid Content of SCP, pp. 17-20, 1977.
J. A. Zee and R. E. Simard, Applied Microbiology, vol. 29, No. 1, pp. 59-62, 1975.

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