Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1988-11-14
1991-04-02
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530381, 435 696, 4352401, 4352402, 4353201, 514 12, 536 27, C07K 1300, C12N 506, C07H 1512, C11N 1564
Patent
active
050048031
ABSTRACT:
Hybrid procoagulant proteins are disclosed which contain peptide sequences of human blood coagulation factors V and VIII. DNA molecules encoding these proteins and materials and methods for expressing them are also disclosed. Preferably, peptide sequence in the B domain of Factor VIII is replaced with peptide sequence derived from human Factor V.
REFERENCES:
Kane, W. et al. (1988) Blood 71(3), 539-555.
Kaufman Randal J.
Pittman Debra
Baker R. Keith
Berstein David
Cserr Luann
Eisen Bruce M.
Genetics Institute Inc.
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