Production of porous tablets

Details Production of porous tablets Production of porous tablets

1976-12-03

1979-01-16

Michl, Paul R.

Plastic and nonmetallic article shaping or treating: processes

With step of cooling to a temperature of zero degrees c. or...

8 79, 264 49, 264101, 264140, 424 14, A61J 310

Patent

active

041349431

ABSTRACT:
Porous tablets are produced by mixing the tablet components with a liquid solvent which is inert towards the components of the tablet and which freezes at a temperature from about -30 to +25.degree. C, the solvent constituting about 5 to 80% by weight of the total mixture, introducing the mixture into an inert cooling medium at a temperature low enough to solidify the solvent, pressing the mixture including the solidified solvent into tablets at a temperature below the freezing point of the solvent, and then evaporating the solvent from the tablets. Advantageously the solvent is water, cyclohexane, benzene and/or tert.-butanol, optionally containing alcohol. The tablets readily disintegrate in liquid.

REFERENCES:
patent: 2877159 (1959-03-01), Lachman
patent: 3607753 (1971-09-01), Suchoff
patent: 3789119 (1974-01-01), Fusari
patent: 3812224 (1974-05-01), Smith
patent: 3885026 (1975-05-01), Heinemann

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