Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2011-06-28
2011-06-28
Steadman, David J (Department: 1656)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S320100, C435S252300, C435S254110, C536S023100, C536S023740
Reexamination Certificate
active
07968312
ABSTRACT:
The present invention relates to polypeptides that have an activity corresponding to at least one activity of the SEC61 polypeptide, polynucleotides encoding these polypeptides and the use thereof in the preparation of host cells suitable for production of a polypeptide of interest. Such host cells may have an increased capacity to secrete a polypeptide of interest.
REFERENCES:
patent: 6344341 (2002-02-01), Keranen et al.
patent: 2003/0119013 (2003-06-01), Jiang et al.
patent: 2004/0025202 (2004-02-01), Laurie et al.
patent: 99/02716 (1999-01-01), None
patent: 02/086090 (2002-10-01), None
patent: 2004/067709 (2004-08-01), None
International Search Report for PCT/EP2005/052805 mailed Nov. 8, 2005.
Cao et al. “The general protein secretory pathway: Phylogenetic analyses leading to evolutionary conclusions” Biochim. Biophys. Acta 1609:115-125 (Jan. 2003).
Conesa et al. “The secretion pathway in filamentous fungi: A biotechnological view” Fungal Gen. Biol. 33:155-171 (2001).
Gouka et al. “Efficient production of secreted proteins byAspergillus: Progress, limitations and prospects” Appl. Microbiol. Biotechnol. 47:1-11 (1997).
Punt et al. “Filamentous fungi as cell factories for heterologous protein production” Trends in Biotechnol. 20:200-206 (2002).
UniProtKB “Hypothetical protein” Database Accession No. Q5AVF9 (May 2005).
UniProtKB “Protein transport protein SEC61 alpha subunit” Database Accession No. SC61A—NEUCR (Oct. 2004).
UniProtKB “Putative SEC61 (Fragment)” Database Accession No. Q6UP01 (Jul. 2004).
Valkonen et al. “Improvement of foreign-protein production inAspergillus nigervar.awamoriby constitutive induction of the unfolded-protein response” Appl. Environ. Microbiol. 69:6979-6986 (Dec. 2003).
Beishuizen Martina
De Lange Linda
Donkers Serge Petrus
Peij Nöel Nicolaas Maria Elisabeth Van
Sagt Cornelis Maria Jacobus
DSM IP Assets B.V.
Nixon & Vanderhye PC
Steadman David J
LandOfFree
Production of polypeptides by improved secretion does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production of polypeptides by improved secretion, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of polypeptides by improved secretion will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2701867