Production of platelet derived growth factor (PDGF) an muteins t

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4352523, 530399, 530412, C12N 1518

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active

057598150

ABSTRACT:
Native, analog, and mutein species of A and B chains of platelet derived growth factor are produced in prokaryotes, purified, combined, and modified in vitro to produce various active AA, AB, and BB PDGF dimers.

REFERENCES:
patent: 4350687 (1982-09-01), Lipton et al.
patent: 4431739 (1984-02-01), Riggs
patent: 4479896 (1984-10-01), Antoniades
patent: 4530787 (1985-07-01), Shaked et al.
patent: 4572798 (1986-02-01), Koths et al.
patent: 4694073 (1987-09-01), Bentle et al.
patent: 4711847 (1987-12-01), Konig et al.
patent: 4766073 (1988-08-01), Murray et al.
patent: 4782139 (1988-11-01), DiMarchi et al.
patent: 4801542 (1989-01-01), Murray et al.
patent: 4845075 (1989-07-01), Murray et al.
patent: 4849407 (1989-07-01), Murray et al.
Antoniades et al., Proc. Natl. Acad. Sci., 1809-1813 (1979).
Betsholtz et al. (1986) Nature, 320:695-699.
Devare et al., (1984) Cell, 36:43-49.
Derynck et al., (1985) Nature, 316:701-705.
Hannink et al., (1986) J. Cell Biology, 103(6)2311-2322.
Heldin et al., Platelet-derived Growth Factor: Purification and Partial Characterization, 76(8) Proc. Natl. Acad. Sci. USA USA 3722-26 (1979).
Josephs et al. (1984) Science, 225:636-639.
Johnsson et al., (1984) The EMBO Journal, vol. 3, No. 5 921-928.
Raines et al, (1982) Platelet-Derived Growth Factor, 257(9) The Journal of Biological Chemistry, 5154-60 (1982).
Martinet et al., (1987) New England Journal of Medicine.
Vogel et al., (1989) Biochemistry 28:2961-2966.
Wang et al., J. Biological chemistry, pp. 10645-10648 (1984).
Watlaufer, D. (1984) Methods in Enzymology, 107:301-304.
Bolstein et al. (1985) Science 229:1193-1201.
Bowie et al., (1990) Science, 247:1306-1310.
Brot et al. (1983) Archieves of Biochemistry and Biophysics, 73(i):271-281.
Hoppe et al. (1987) "Preparation of Biologically Active PDGF B from a Fusion Protein Express in E. Coli"abstract presented at Symposium on Growth Factors and Their Reactions, Sponsored by European School of Oncology.
Wane, Jean Y.J. & Lewis T. Williams. "Av-sisoncogene Protein Produced in Bacteria Competes for Platelet-Derived Growth Factor-Binding to Its Receptor." J. Biol. Chem 259:10645-10648, 1984.
Wetlaufer, D. "Nonenzymatic-Formation and Isomerization of Protein Disulfides" Methods in Enzymology 107:301-304, 1984.

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