Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1991-05-06
1998-06-02
Spector, Lorraine
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 530399, 530412, C12N 1518
Patent
active
057598150
ABSTRACT:
Native, analog, and mutein species of A and B chains of platelet derived growth factor are produced in prokaryotes, purified, combined, and modified in vitro to produce various active AA, AB, and BB PDGF dimers.
REFERENCES:
patent: 4350687 (1982-09-01), Lipton et al.
patent: 4431739 (1984-02-01), Riggs
patent: 4479896 (1984-10-01), Antoniades
patent: 4530787 (1985-07-01), Shaked et al.
patent: 4572798 (1986-02-01), Koths et al.
patent: 4694073 (1987-09-01), Bentle et al.
patent: 4711847 (1987-12-01), Konig et al.
patent: 4766073 (1988-08-01), Murray et al.
patent: 4782139 (1988-11-01), DiMarchi et al.
patent: 4801542 (1989-01-01), Murray et al.
patent: 4845075 (1989-07-01), Murray et al.
patent: 4849407 (1989-07-01), Murray et al.
Antoniades et al., Proc. Natl. Acad. Sci., 1809-1813 (1979).
Betsholtz et al. (1986) Nature, 320:695-699.
Devare et al., (1984) Cell, 36:43-49.
Derynck et al., (1985) Nature, 316:701-705.
Hannink et al., (1986) J. Cell Biology, 103(6)2311-2322.
Heldin et al., Platelet-derived Growth Factor: Purification and Partial Characterization, 76(8) Proc. Natl. Acad. Sci. USA USA 3722-26 (1979).
Josephs et al. (1984) Science, 225:636-639.
Johnsson et al., (1984) The EMBO Journal, vol. 3, No. 5 921-928.
Raines et al, (1982) Platelet-Derived Growth Factor, 257(9) The Journal of Biological Chemistry, 5154-60 (1982).
Martinet et al., (1987) New England Journal of Medicine.
Vogel et al., (1989) Biochemistry 28:2961-2966.
Wang et al., J. Biological chemistry, pp. 10645-10648 (1984).
Watlaufer, D. (1984) Methods in Enzymology, 107:301-304.
Bolstein et al. (1985) Science 229:1193-1201.
Bowie et al., (1990) Science, 247:1306-1310.
Brot et al. (1983) Archieves of Biochemistry and Biophysics, 73(i):271-281.
Hoppe et al. (1987) "Preparation of Biologically Active PDGF B from a Fusion Protein Express in E. Coli"abstract presented at Symposium on Growth Factors and Their Reactions, Sponsored by European School of Oncology.
Wane, Jean Y.J. & Lewis T. Williams. "Av-sisoncogene Protein Produced in Bacteria Competes for Platelet-Derived Growth Factor-Binding to Its Receptor." J. Biol. Chem 259:10645-10648, 1984.
Wetlaufer, D. "Nonenzymatic-Formation and Isomerization of Protein Disulfides" Methods in Enzymology 107:301-304, 1984.
Babickas Zita A.
Charette Marc F.
Oppermann Hermann
Creative BioMolecules, Inc.
Spector Lorraine
LandOfFree
Production of platelet derived growth factor (PDGF) an muteins t does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production of platelet derived growth factor (PDGF) an muteins t, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of platelet derived growth factor (PDGF) an muteins t will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1458534