Production of picolinic acid and pyridine products via pseudomon

Details Production of picolinic acid and pyridine products via pseudomon Production of picolinic acid and pyridine products via pseudomon

1985-07-26

1989-08-22

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

4352533, 435877, C12P 1712, C12N 120, C12R 140

Patent

active

048595926

ABSTRACT:
This invention provides a process for the bioconversion of a non-growth aromatic feed to an accumulated quantity of a picolinic acid product with reduced accumulation of 2-hydroxymuconic semialdehyde, and conducted in the presence of ammonium or a primary amine, which acid subsequently can be converted by chemical means to a pyridine product.

REFERENCES:
patent: 4654303 (1987-03-01), Hagedorn
patent: 4666841 (1989-05-01), Hagedorn
patent: 4673646 (1987-06-01), Hagedorn
Dagley, et al., "New Pathways in the Oxidative Metabolism of Aromatic Compounds by Micro-Organisms"; Nature, V. 188, pp. 560-566 (1960).
Moser et al., "Decarboxylation of 5-Substituted-2-Pyridinecarboxylic Acids", J. Org. Chem., V. 37, No. 24, pp. 3938-3940 (1972).

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