Production of picolinic acid and pyridine products

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435253, 4351723, 435877, 435128, 435146, C12P 1300, C12N 1500, C12N 120, C12R 140

Patent

active

046668411

ABSTRACT:
This invention provides a process for the bioconversion of a non-growth aromatic feed to an accumulated quantity of a 2-hydroxymuconic semialdehyde intermediate, which subsequently is converted by chemical means to picolinic acid and pyridine products.

REFERENCES:
Dagley et al, 1960, "New Pathways in the Oxidative Metabolism of Aromatic Compounds by Microorganisms", Nature, v 188, 560-566.
Davis et al, 1968, "Metabolism of P- and M-Xylene by Species of Pseudomonas", Can. J. Micro., v 14, 1005-1009.
Moser et al, 1972, "Decarboxylation of 5-Substituted 2-Pyridine-Carboxylic Acids", J. Org. Chem., v 37, 3938-3942.

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