Production of orthomyxoviruses in monkey kidney cells using prot

Details Production of orthomyxoviruses in monkey kidney cells using prot Production of orthomyxoviruses in monkey kidney cells using prot

1997-10-15

2000-11-14

Lankford, Jr., Leon B.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

435239, 435237, 435325, 435364, 424 936, 4242091, C12N 701, C12N 708

Patent

active

061468738

ABSTRACT:
Viruses from the family Orthomyxoviridae, particularly influenza virus, can grown in monkey kidney cells, particularly Vero Cells, after passaging the cells in a serum-free or protein-free medium. The use of a proteolytic enzyme, especially trypsin, also aids in the propagation of the virus. The method allows for the virus to be produced to be used in a vaccine.

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