Production of nanaomycin B

Details Production of nanaomycin B Production of nanaomycin B

1977-12-07

1980-03-18

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435127, 435132, 435146, 435147, 435156, 435169, 435886, 2603452, 424181, C12D 914

Patent

active

041940644

ABSTRACT:
The present invention relates to new compound designated as nanaomycin B represented by general formula: ##STR1## Nanaomycin B is a quinone type and is active on mycoplasma, Gram-positive bacteria and trycophyton. This compound is useful as a medicament for infectious diseases of humans and animals caused by a parasite of trichophyton or mycoplasma etc. The acute toxicity (LD.sub.50, intra-penetrial injection) in mice of this compound is 169 mg/kg. Nanaomycin B is produced by fermentation in which a nanaomycin-producing strain belonging to the genus Streptomyces is cultured in a medium under aerobic conditions and the accumulated nanaomycin B in the cultured broths is recovered therefrom.

REFERENCES:
patent: 3817835 (1974-06-01), Neidleman
patent: 3833556 (1974-09-01), Shier et al.
patent: 4003902 (1977-01-01), Kluepfel et al.
patent: 4036696 (1977-07-01), Stapley et al.
Tanaka et al., Nanaomycins, New Antibiotics Produced by a Strain of Streptomyces, Journal of Antibiotics, vol. 28, No. 12, 1975, (pp. 925-930).

Affiliated with

Also associated with

Rating

Production of nanaomycin B does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Production of nanaomycin B, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of nanaomycin B will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1124805