Production of monatin enantiomers

Details Production of monatin enantiomers Production of monatin enantiomers

2011-08-23

2011-08-23

Desai, Anand (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S004000, C435S118000, C435S121000, C548S497000, C548S494000, C548S240000

Reexamination Certificate

active

08003361

ABSTRACT:
Methods for preferentially hydrolyzing one stereoisomer of an isoxazoline diester over another, as well as an enzyme for facilitating the preferential hydrolysis are provided. Also provided are methods for providing mixtures of (RR) and (RS) monatin as well as (SS) and (SR) monatin, which methods can include the step of stereoselectively hydrolyzing an isoxazoline diester.

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