Production of mixtures rich in 6-chloro-2-trichloromethyl pyridi

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D21360

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044879350

ABSTRACT:
Preparation of high yields of mixtures rich in 6-chloro-2-trichloromethyl pyridine by maintaining a chlorine to alpha-picoline weight ratio of greater than about 8:1 when feeding alpha-picoline hydrochloride and excess chlorine to reactor means at a temperature in the range of about 170.degree. C. to about 250.degree. C. in the absence of a catalyst, the reactants being contained in a well mixed diluent producing essentially no hydrogen chloride by reaction with chlorine in the indicated temperature range.

REFERENCES:
patent: 3135594 (1964-09-01), Goring
patent: 3256167 (1966-06-01), Norton et al.
patent: 3420833 (1969-01-01), Taplin
patent: 3424754 (1969-01-01), Taplin
patent: 4256894 (1981-03-01), Dietsche et al.
Pesticide Manufacturing and Toxic Materials Control Encyclopedia (1980), pp. 559-561).
Affidavit Under Rule 131 by William H. Taplin III, dated Nov. 28, 1967, (located in file history of Taplin U.S. Pat. No. 3,424,754).
Kosorotov et al., Zhurnal Organischeskoi Khimii, vol. 16, No. 10, pp. 2163-2171, Oct. 1980 (English Translation).
William James Sell, J. Chem. Soc., vol. 87, pp. 799 et seq. (1905).

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