Production of microcapsules of water-soluble drugs

Plastic and nonmetallic article shaping or treating: processes – Encapsulating normally liquid material – Liquid encapsulation utilizing an emulsion or dispersion to...

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264 46, B01J 1302, B01J 1304

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active

056119712

ABSTRACT:
There is provided a process for producing microcapsules of a water-soluble drug by in-water drying process, which comprises carrying out the process in the presence of an osmotic pressure adjustor present in the external aqueous phase. This process improves the drug take up into microcapsules.

REFERENCES:
patent: 3703576 (1972-11-01), Kitajima et al.
patent: 3891570 (1975-06-01), Fukushimal et al.
patent: 4954298 (1990-09-01), Yamamoto et al.
K. Thoma et al., "beziehungen sqischen herstellungeparametern und pharmazcutisch-technologischen anforderungen an biodegradierbare mikropartikeln" DIE PHARMAZIE, vol. 47, No. 2, Feb. '92, pp. 115-119.

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